The Nilotic peoples—the Dinka, Nuer, Shilluk and others—first entered South Sudan sometime before the 10th century. During the period from the 15th to the 19th centuries, tribal migrations, largely from the area of Bahr el Ghazal, brought these peoples to their modern locations. The non-Nilotic Azande people, who entered South Sudan in the 16th century, established the region's largest state.      The Azande are the third- or fourth-largest ethnic group in South Sudan (either the Azande or the Bari are third-largest). They are found in the Maridi, Yambio, and Tambura districts in the tropical rainforest belt of Western Equatoria and Western Bahr el Ghazal. In the 18th century, the Avungara sib rose to power over the rest of Azande society and this domination continued into the 20th century. Geographical barriers prevented the spread of Islam to the southerners, thus enabling them to retain their social and cultural heritage, as well as their political and religious institutions.

     The Azande have had difficult relations with the neighbours, namely the Moru, Mundu, Pöjulu, and the small groups in Bahr el Ghazal, due to the expansionist policy of their king, Gbudwe, in the 18th century. In the 19th century, the Azande fought the French, the Belgians and the Mahdists to maintain their independence.